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TY - JOUR AU - Avilés, Josué Nicanor Díaz AU - Méndez, José Luis Alanís AU - Medrano, Nahim Salgado AU - Taketa, Alexandre Tochirico Cardoso AU - Florescano, Ivette Alicia Chamorro AU - Díaz, Oswaldo Javier Enciso PY - 2020/12/10 Y2 - 2025/09/23 TI - Phytochemical screening, antioxidant activity and toxicity of the orchids Prosthechea cochleata and Prosthechea livida-A preliminary study JF - Journal of Medicinal Herbs and Ethnomedicine JA - JMHE VL - 6 IS - 0 SE - Articles DO - 10.25081/jmhe.2020.v6.6431 UR - https://www.updatepublishing.com/journal/index.php/jmhe/article/view/6431 SP - 117-122 AB - <p style="text-align: justify;">Phytochemical composition, antioxidant, and toxic effects of two orchid <em>(Prosthechea</em> <em>cochleata </em>and<em> Prosthechea</em> <em>livida</em>) were examined in their different hexane and dichloromethane/methanol extracts of leaves, pseudobulbs, rhizome and roots. &nbsp;Phytochemical screening reveals the presence of alkaloids, coumarins, flavonoids, saponins, steroids and terpenes except for anthracene derivatives in <em>P. livida</em> and tannins in both species. Results showed exhibited significant toxicity against brine shrimp with an LC₅₀ values ranged from 3 to 54 µg/ml in 24 h.&nbsp; Finally, the results of the antioxidant test in yeast (<em>Saccharomyces cerevisiae</em>) showed that CH₂Cl₂:MeOH extract of <em>P. cochleata</em> root extract presented the most efficient protective antioxidant percentage (%PA), with 20 µg/mL, displaying a cell viability of 68.58%. In <em>P. livida</em> case, rhizome extract presented the most efficient %PA, with 1000 µg/mL, with a cell viability of 65.82%.&nbsp; The results evidenced the toxicity of <em>&nbsp;Prosthechea cochleata</em> and <em>Prosthechea livida </em>and reveals potential antioxidative of extracts.</p> ER -