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TY - JOUR AU - Singh, Anmol AU - Palariya, Diksha AU - Dhami, Anamika AU - Prakash, Om AU - Kumar, Ravendra AU - Rawat, Dharmendra Singh AU - Pant, Anil Kumar PY - 2020/01/21 Y2 - 2025/09/23 TI - Biological activities and Phytochemical analysis of Zanthoxylum armatum DC. leaves and bark extracts collected from Kumaun region, Uttarakhand, India JF - Journal of Medicinal Herbs and Ethnomedicine JA - JMHE VL - 6 IS - 0 SE - Articles DO - 10.25081/jmhe.2020.v6.5754 UR - https://www.updatepublishing.com/journal/index.php/jmhe/article/view/5754 SP - 1-10 AB - <p>The methanolic and chloroform extracts of leaves and bark of <em>Zanthoxylum armatum</em> DC. were evaluated for their phytochemical analysis and biological activities. In phytochemical analysis, fargsin was identified as major constituent in leaves methanolic and leaves chloroform extracts. t-butylamine and benzoxazole, 2-(isobutylamino) were identified as the major constituents in bark methanolic and bark chloroform extracts respectively. Both the extracts exhibited moderate antioxidant activity with IC₅₀values ranging from 19.42±0.07 to78.01±0.31 µg. These extracts also possess moderate anti-inflammatory activity with IB₅₀ values ranging from 28.53 ± 0.06 to 89.80 ± 0.05 µg. Moderate anti-bacterial activity against <em>E. coli</em> and <em>S. aureus</em> has also been observed in both the extracts. The total flavonoids, orthodihydric phenols and phenolic contents were also quantified in the extracts. Based on these observations, it can be concluded that <em>Zanthoxylum armatum</em> DC. may be used as herbal antioxidant, food preservative, natural anti-inflammatory drug and natural bactericidal, besides generation of data base for judicious exploitation in future.</p> ER -