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TY  - JOUR
AU  - SARFRAZ, R. A.
AU  - S. MURTAZA, Q. U. HASSAN,
PY  - 2018/06/01
Y2  - 2025/09/23
TI  - EFFECT OF DIFFERENT SOLVENTS ON THE CHEMICAL COMPOSITION AND ANTI-DIABETIC ACTIVITY OF ACACIA ARABICA AND ZIZYPHUS MAURITIANA
JF  - Journal of Medicinal Herbs and Ethnomedicine
JA  - JMHE
VL  - 4
IS  - 0
SE  - REGULAR ISSUE ARTICLES
DO  - 10.25081/jmhe.2018.v4.3638
UR  - https://www.updatepublishing.com/journal/index.php/jmhe/article/view/3638
SP  - 35-37
AB  - &lt;p&gt;The current study was designed to investigate the effect of solvents on chemical composition and antidiabetic activity of &lt;em&gt;Zizyphus mauritiana&lt;/em&gt; and &lt;em&gt;Acacia Arabica &lt;/em&gt;extracts. Total five solvents were used for this purpose (100% methanol, 50% aqueous methanol, 100% ethanol, 50% aqueous ethanol and aqueous). The data obtained from the investigation was subjected to the statistical analysis by using analysis of variance technique. The present study revealed that maximum antioxidant activity was attributed to &lt;em&gt;Acacia arabica&lt;/em&gt; (96.53 ± 0.46%) followed by &lt;em&gt;Zizyphus mauritiana&lt;/em&gt; (94.33 ± 0.52% by 50% aqueous ethanol extracts). Maximum total phenolic content of both &lt;em&gt;Zizyphus mauritiana&lt;/em&gt; and &lt;em&gt;Acacia arabica&lt;/em&gt; (670.83 ± 1.46 mg GAE/100g and 934.34 ± 0.89 mg GAE/100g) were shown by 50% aqueous ethanol extracts while maximum total flavonoid content (146.36 ± 0.81 mg QE/100 g, 172.52 ± 0.99 mg QE/100 g) was exhibited by 50% aqueous ethanol extract. The maximum (IC 50= 49.63 ± 0.12 µg/mL) antidiabetic activity was found in aqueous extract of &lt;em&gt;Acacia arabica&lt;/em&gt; while in &lt;em&gt;Zizyphus mauritiana&lt;/em&gt; the aqueous extract indicated excellent (IC 50= 46.90 ± 0.23 µg/mL) antidiabetic activity.&lt;/p&gt;
ER  -