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TY  - JOUR
AU  - Markandeya2, D.A. Dhale1* and S.K.
PY  - 2011/02/26
Y2  - 2025/09/23
TI  - Antimicrobial and Phytochemical Screening of Plumbago zeylanica Linn. (Plumbaginaceae) Leaf
JF  - Journal of Experimental Sciences
JA  - JES
VL  - 2
IS  - 3
SE  - Life Sciences
DO  - 
UR  - https://www.updatepublishing.com/journal/index.php/jes/article/view/1811
SP  - 
AB  - &lt;div style=&quot;border-right: medium none; padding-right: 0in; border-top: windowtext 1pt solid; padding-left: 0in; background: white; padding-bottom: 0in; border-left: medium none; padding-top: 1pt; border-bottom: medium none; mso-element: para-border-div; mso-border-top-alt: solid windowtext .5pt;&quot;&gt;&lt;p class=&quot;MsoNormal&quot; style=&quot;background: white; margin: 6pt 0in 0pt; text-align: justify; mso-border-top-alt: solid windowtext .5pt; mso-padding-alt: 1.0pt 0in 0in 0in; padding: 0in;&quot;&gt;&lt;span style=&quot;font-size: 8pt; font-family: &quot;;Tahoma&quot;;,&quot;;sans-serif&quot;;;&quot;&gt;The antimicrobial effect of&lt;strong style=&quot;mso-bidi-font-weight: normal;&quot;&gt;&lt;em style=&quot;mso-bidi-font-style: normal;&quot;&gt;&lt;span style=&quot;color: black;&quot;&gt; &lt;/span&gt;&lt;/em&gt;&lt;/strong&gt;&lt;em style=&quot;mso-bidi-font-style: normal;&quot;&gt;&lt;span style=&quot;color: black;&quot;&gt;Plumbago zeylanica &lt;/span&gt;&lt;/em&gt;&lt;span style=&quot;color: black;&quot;&gt;Linn. (Plumbaginaceae)&lt;/span&gt; leaf extract was evaluated on microbial strains like &lt;span style=&quot;color: black;&quot;&gt;gram positive species &lt;/span&gt;&lt;em&gt;Staphylococcus aureus&lt;/em&gt;&lt;span style=&quot;color: black;&quot;&gt;, and &lt;/span&gt;&lt;em&gt;Bacillus subtilis&lt;/em&gt;&lt;span style=&quot;color: black;&quot;&gt; and gram negative species &lt;/span&gt;&lt;em&gt;Escherichia coli&lt;/em&gt;&lt;span style=&quot;color: black;&quot;&gt; and &lt;/span&gt;&lt;em&gt;Pseudomonas aeruginosa.&lt;/em&gt;&lt;span style=&quot;color: black;&quot;&gt; The solvent used for extraction of plant were petroleum ether, &lt;/span&gt;chloroform and alcohol. &lt;span style=&quot;color: black;&quot;&gt;The alcoholic extract of leaves of &lt;em style=&quot;mso-bidi-font-style: normal;&quot;&gt;Plumbago zeylanica&lt;/em&gt; shows maximum antimicrobial activity. The &lt;em style=&quot;mso-bidi-font-style: normal;&quot;&gt;in vitro&lt;/em&gt; antimicrobial evaluation was carried out by agar disc diffusion method. The significant antibacterial activity of active extract was compared with standard antibiotic &lt;/span&gt;Amphicillin. &lt;span style=&quot;color: black;&quot;&gt;&lt;span style=&quot;mso-spacerun: yes;&quot;&gt;Ã‚Â &lt;/span&gt;The &lt;/span&gt;samples of leaves &lt;span style=&quot;color: black;&quot;&gt;were further used for the &lt;span class=&quot;yshortcuts&quot;&gt;phytochemical studies&lt;/span&gt;. Results of the phytochemical analysis indicated the presence of &lt;/span&gt;alkaloids, glycoside, reducing sugars, simple phenolics, tannins, Lignin, saponins and flavonoids&lt;span style=&quot;color: black;&quot;&gt;. The antibacterial activities of the leaves were due to the presence of various &lt;span class=&quot;yshortcuts&quot;&gt;secondary metabolites.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;&lt;/div&gt;
ER  -